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Meet the Team

Group Leader

PD Dr. Martin Breugst
mbreugst(at)uni-koeln.de
Tel: +49 221 470 3294

Martin got his undergraduate education in chemistry and biochemistry from the Ludwig-Maximilians-University in Munich, Germany. After obtaining his Master's degree in 2006, he pursued graduate studies with Herbert Mayr in physical organic chemistry working on ambident reactivity and kinetics. In 2011, Martin moved to the University of California, Los Angeles as a Feodor-Lynen postdoctoral fellow where he worked with Ken Houk on different aspects of computational organic chemistry. Since 2013, Martin works at the Department of Chemistry at the University of Cologne as an independent researcher and completed his habilitation there in 2017. In 2018/9, Martin additionally serves as a substitute professor for organic chemistry at the University of Regensburg. Furthermore, he was elected to the board of the Junior Faculty Club in 2017 as the representative of the Faculty of Mathematics and Natural Sciences of the University of Cologne.

Graduate Students

Mikk Kaasik
mkaasik(at)uni-koeln.de
Tel: +49 221 470 3250

Mikk studied chemistry at Tallinn University of Technology. During his Master studies he spent a semester at the Royal Institute of Technology in Stockholm. In 2015 he received a Master’s degree from Tallinn University of Technology investigating the conjugate addition of a cyclopropylacetaldehyde derivative. In 2015 he started his doctoral studies under the supervision of Prof. Tõnis Kanger on the topic of novel asymmetric catalytic reactions. In October 2018 he joined Martin Breugst’s research group for an eight month research stay.

Publications:

Synthesis and Characterisation of Chiral Triazole-Based Halogen-Bond Donors: Halogen Bonds in the Solid State and in Solution
M. Kaasik, S. Kaabel, K. Kriis, I. Järving, R. Aav, K. Rissanen, T. Kanger, Chem. Eur. J., 2017, 23, 7337−7344.
DOI (English Version): 10.1002/chem.201700618

Organocatalytic Conjugate Addition of Cyclopropylacetaldehyde Derivatives to Nitro Olefins: en Route to β- and γ-Amino Acids
M. Kaasik, A. Noole, K. Reitel, I. Järving, T. Kanger, Eur. J. Org. Chem., 2015, 1745−1753.
DOI (Deutsche Version): 10.1002/ejoc.201403387

Jonas König
jonas.koenig(at)uni-koeln.de
Tel: +49 221 470 3250

Jonas studied chemistry at the RWTH Aachen, Germany. After an internship with Sanofi Deutschland in Frankfurt a. M., he received his Master’s degree in Aachen in 2016 working on insertion reaction of diazomethane compounds. In 2016 he joined Martin Breugst’s research group as a graduate student.

Publications:

Redetermination of the Solvent-Free Crystal Structure of L-Proline
J. J. König, J.-M. Neudörfl, A. Hansen, M. Breugst, Acta Crystallogr., Sect. E: Crystallogr. Commun., 2018, E74, 1067–1070.
DOI (English Version): 10.1107/S2056989018009490

Sperrige Substituenten – Zwischen Attraktion und Repulsion
J. J. König, M. Breugst, Nachr. Chem., 2018, 66, 505–509.
DOI (Deutsche Version): 10.1002/nadc.20184073225

Julie Pieper gen. Schmauck
jpieper6(at)uni-koeln.de
Tel: +49 221 470 4375

Julie studied chemistry at the University of Cologne, Germany. During her master’s programme she spent 3 months in Graz, Austria working on biocatalysis. She did her Master thesis at the Imperial College London, UK working on ion solubility in ionic liquids using computational methods and received her Master’s degree in Cologne in 2015. In 2015 she joined Martin Breugst's research group as a graduate student and is the recipient of the 2016 Hoechst Doktorandenstipendium.

Publications:

Katalyse mit elektrophilen Phosphoniumionen
J. Schmauck, M. Breugst, Nachr. Chem., 2018, 66, 862.
DOI (Deutsche Fassung): 10.1002/nadc.20184077309

Electron Beam Immobilization of Novel Antimicrobial, Short Peptide Motifs Leads to Membrane Surfaces with Promising Antibacterial Properties
A. Reinhardt, I. Thomas, J. Schmauck, R. Giernoth, A. Schulze, I. Neundorf, J. Funct. Biomater., 2018, 9, 21.
DOI (English Version): 10.3390/jfb9010021

The potential of pnicogen bonding for catalysis – A computational study
J. Schmauck, M. Breugst, Org. Biomol. Chem., 2017, 15, 8037–8045.
DOI (English Version): 10.1039/C7OB01599B

Novel Noncovalent Interactions in Catalysis: A Focus on Halogen, Chalcogen, and Anion-π Bonding
M. Breugst, D. von der Heiden, J. Schmauck, Synthesis, 2017, 49, 3224–3236.
DOI (English Version): 10.1055/s-0036-1588838

Highly Enantioselective Allylation of Ketones - An Efficient Approach to all Stereoisomers of Tertiary Homoallylic Alcohols
M. Brauns, M. Mantel, J. Schmauck, M. Guder, M. Breugst, J. Pietruszka, Chem. Eur. J., 2017, 23, 12136–12140.
DOI (English Version): 10.1002/chem.201701740

Solubility of Alkali Metal Halides in the Ionic Liquid [C4C1im][OTf]
O. Kuzmina, E. Bordes, J. Schmauck, P. A. Hunt, J. P. Hallet, T. Welton, Phys. Chem. Chem. Phys., 2016, 18, 16161–16168.
DOI (English Version): 10.1039/c6cp02286c

Novel Imidazolium Salt-Peptide Conjugates and Their Antimicrobial Activity
A. Reinhardt, M. Horn, J. Schmauck, A. Bröhl, R. Giernoth, C. Oelkrug, A. Schubert, I. Neundorf, Bioconjug. Chem., 2014, 25, 2166–2174.
DOI (English Version): 10.1021/bc500510c

Undergraduate Students

    Eric Detmar
    edetmar1(at)uni-koeln.de
    Tel: +49 221 470 4375

    Eric joined Martin Breugst's group in January 2015 for his Bachelor thesis. After graduation, he stayed in the group working as a student assistant. Eric is currently developing a large variety of python scripts that will facilitate the evaluation of our computational studies.

    Publications:

    Cobalt-Catalyzed C–H Cyanations: Insights into the Reaction Mechanism and the Role of London Dispersion
    E. Detmar, V. Müller, D. Zell, L. Ackermann, M. Breugst, Beilstein J. Org. Chem., 2018, 14, 1537–1545.
    DOI (English Version): 10.3762/bjoc.14.130

    Activation of Michael Acceptors by Halogen-Bond Donors
    D. von der Heiden, E. Detmar, R. Kuchta, M. Breugst, Synlett, 201829, 1307–1313.
    DOI (English Version): 10.1055/s-0036-1591841

    Determination of the residual entropy of simple mixtures by Monte Carlo simulation
    E. Detmar, S. Yazdi Nezhad, U. K. Deiters Langmuir. 2017, 33, 11603–11610.
    DOI (English Version) 10.1021/acs.langmuir.7b02000

    Origin of the Catalytic Effects of Molecular Iodine – A Computational Analysis
    M. Breugst, E. Detmar, D. von der Heiden ACS Catal. 2016, 6, 3203–3212.
    DOI (English Version) 10.1021/acscatal.6b00447

    Interested in Joining the Group?

    Students and post-doctoral researchers have the unique opportunity to explore an area of their interest and can gain synthetic skills in organic synthesis and/or will become experts in the computational analysis of reaction mechanisms by density functional theory.

    Currently, there are opportunities for students who want to do their Bachelor or Master thesis or "Forschungspraktika" (E or P-Module) in our group. We offer a broad range of different projects tailored to your interests – from purely synthetic organic chemistry via kinetic studies to computational investigations.

    We happily assist highly motivated students with scholarship applications.

    Alumni


    Dr. Daniel von der Heiden (PhD in 2018)

    Daniel studied chemistry at the Westfälische Wilhelms-Universität in Münster, Germany. After an internship with Boehringer Ingelheim in Vienna, Austria, he received his Master’s degree in Münster in 2014 working on the selective metalation of chlorazoles and imidazolium salts. In 2015 he joined Martin Breugst’s research group as a graduate student and obtained his PhD in April 2018. In May 2018, Daniel furthermore received the Kurt-Alder award for his outstanding PhD thesis.

    Publications:

    Mechanisms in Iodine Catalysis
    M. Breugst, D. von der Heiden, Chem. Eur. J., 201824, 9187–9199.
    DOI (English Version): 10.1002/chem.201706136

    Activation of Michael Acceptors by Halogen-Bond Donors
    D. von der Heiden, E. Detmar, R. Kuchta, M. Breugst, Synlett, 2018, 29, 1307–1313.
    DOI (English Version): 10.1055/s-0036-1591841

    Novel Noncovalent Interactions in Catalysis: A Focus on Halogen, Chalcogen, and Anion-π Bonding
    M. Breugst, D. von der Heiden, J. Schmauck, Synthesis, 2017, 49, 3224–3236.
    DOI (English Version): 10.1055/s-0036-1588838

    Reaction Mechanism of Iodine-Catalyzed Michael Additions
    D. von der Heiden, S. Bozkus, M. Klussmann, M. Breugst J. Org. Chem. 2017, 82, 4037–4043.
    DOI (English Version): 10.1021/acs.joc.7b00445

    Origin of the Catalytic Effects of Molecular Iodine – A Computational Analysis
    M. Breugst, E. Detmar, D. von der Heiden ACS Catal. 2016, 6, 3203–3212.
    DOI (English Version): 10.1021/acscatal.6b00447

    Bachelor-Thesis

    • Thomas Anklam (2018)
    • Seyma Bozkus (2016)
    • Benedict Braunsfeld (2018)
    • Nadine Dernbach (2018)
    • Eric Detmar (2015)
    • Lukas Neu (2016)
    • Julia Olenburger (2015)
    • Łukasz Osika (2017)
    • Luise Schäfer (2017)

     Master-Thesis

    • Max Hasenbeck (2017, Heinrich-Heine-University Düsseldorf)
    • Simon Herkenhöhner (2016)